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Basic information about DOSTINEX 0.5MG 2TAB. ·          Active content: CABERGOLINE . ·          Price: 65   LE   for   2 tablets. ·          Medical classification: hyperprolactinemic disorders, opamine D2 receptors agonist. ·          Company: PFIZER, EGYPT . DOSTINEX 0.5MG 2TAB. Description  Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors. DOSTINEX 0.5MG 2TAB. Indication                For the treatment of hyperprolactinemic disorders, either idiopathic or due to prolactinoma (prolactin-secreting adenomas).  May also be used to manage symptoms of Parkinsonian Syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease. Mechanism of action The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated w

Basic information about DIFLUCAN 150MG 1 CAPS. ·          Active content: FLUCONAZOLE. ·          Price: 32.4   LE   for   1 capsules. ·          Medical classification: antifungals.Triazoles. ·          Company: PFIZER, EGYPT . Mechanism of Action of DIFLUCAN 150mg 1 Caps. Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. DIFLUCAN 150mg 1 Caps. Interactions 1.        Cimetidine : Decreased efficacy of fluconazole. 2.        Cyclosporine : Increase in serum cyclosporine plasma concentration. 3.        Hydrochlorothiazide : Reduction in renal clearance of fluconazole. 4.        Phenytoin : Efficacy of phenytoin enhanced. 5.        Rifampicin : Efficacy of fluconazole decreased, higher dosage required. 6.        Sulfonylureas : Efficacy of tolbutamide, glyburide and glipizide increased. 7.        War

Basic information about DIFLUCAN 5MG/ML 70ML SYRUP ·          Active content: FLUCONAZOLE. ·          Price: 68   LE   for   70 ml. ·          Medical classification: antifungals.Triazoles. ·          Company: PFIZER, EGYPT . Mechanism of Action of DIFLUCAN 5mg/ml 70ml syrup Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. DIFLUCAN 5mg/ml 70ml syrup Interactions 1.        Cimetidine : Decreased efficacy of fluconazole. 2.        Cyclosporine : Increase in serum cyclosporine plasma concentration. 3.        Hydrochlorothiazide : Reduction in renal clearance of fluconazole. 4.        Phenytoin : Efficacy of phenytoin enhanced. 5.        Rifampicin : Efficacy of fluconazole decreased, higher dosage required. 6.        Sulfonylureas : Efficacy of tolbutamide, glyburide and glipizide increased. 7.      

Basic information about DIFLUCAN 50MG 7CAPS. ·          Active content: FLUCONAZOLE. ·          Price: 68   LE   for   7 capsules. ·          Medical classification: antifungals.Triazoles. ·          Company: PFIZER, EGYPT . Mechanism of Action of DIFLUCAN 50mg 7Caps. Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. DIFLUCAN 50mg 7Caps. Interactions 1.        Cimetidine : Decreased efficacy of fluconazole. 2.        Cyclosporine : Increase in serum cyclosporine plasma concentration. 3.        Hydrochlorothiazide : Reduction in renal clearance of fluconazole. 4.        Phenytoin : Efficacy of phenytoin enhanced. 5.        Rifampicin : Efficacy of fluconazole decreased, higher dosage required. 6.        Sulfonylureas : Efficacy of tolbutamide, glyburide and glipizide increased. 7.        Warfarin :

Basic information about DIFLUCAN 2MG/ML (100ML) I.V. INFUSION ·          Active content: FLUCONAZOLE. ·          Price: 70   LE   for   100 vial. ·          Medical classification: antifungals.Triazoles. ·          Company: PFIZER, EGYPT . Mechanism of Action of DIFLUCAN 2mg/ml (100ml) I.V. infusion Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. DIFLUCAN 2mg/ml (100ml) I.V. infusion Interactions 1.        Cimetidine : Decreased efficacy of fluconazole. 2.        Cyclosporine : Increase in serum cyclosporine plasma concentration. 3.        Hydrochlorothiazide : Reduction in renal clearance of fluconazole. 4.        Phenytoin : Efficacy of phenytoin enhanced. 5.        Rifampicin : Efficacy of fluconazole decreased, higher dosage required. 6.        Sulfonylureas : Efficacy of tolbutamide, glyburi

Basic information about DETRUSITOL RETARD 4MG PROLONGED RELEASE 7CAPS. ·          Active content: TOLTERODINE L TARTARATE. ·          Price: 65   LE   for   7 capsules. ·          Medical classification: Urinary incontinence.Antispasmodics.Muscarinic Antagonists. ·          Company: PFIZER, EGYPT . Mechanism of Action of DETRUSITOL RETARD 4mg prolonged release 7Caps. Tolterodine tartrate is a specific muscarinic receptor (M3 receptor) antagonist. It blocks muscarinic receptors which can be found on the muscle cells of the bladder wall.  It prevents the action of acetyl choline on these receptors. Acetylcholine acting on these receptors causes the muscle in the bladder wall to contract, and the bladder to empty. By preventing this, Tolterodine helps the muscle in the bladder wall to relax. This reduces unstable, involuntary contractions of the bladder, and thereby increases the capacity of the bladder to hold urine. This in turn reduces the need to pass urine. Stimulation of muscarinic

Basic information about DIFLUCAN 2MG/ML (50ML) I.V. INFUSION ·          Active content: FLUCONAZOLE. ·          Price: 40   LE   for   50 vial. ·          Medical classification: antifungals.Triazoles. ·          Company: PFIZER, EGYPT . Mechanism of Action of DIFLUCAN 2mg/ml (50ml) I.V. infusion Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. DIFLUCAN 2mg/ml (50ml) I.V. infusion Interactions 1.        Cimetidine : Decreased efficacy of fluconazole. 2.        Cyclosporine : Increase in serum cyclosporine plasma concentration. 3.        Hydrochlorothiazide : Reduction in renal clearance of fluconazole. 4.        Phenytoin : Efficacy of phenytoin enhanced. 5.        Rifampicin : Efficacy of fluconazole decreased, higher dosage required. 6.        Sulfonylureas : Efficacy of tolbutamide, glyburide a