DIFLUCAN 150MG 1 CAPS.
Basic information about DIFLUCAN 150MG 1 CAPS.
· Active content: FLUCONAZOLE.
· Price: 32.4 LE for 1 capsules.
· Medical classification: antifungals.Triazoles.
· Company: PFIZER, EGYPT .
Mechanism of Action of DIFLUCAN 150mg 1 Caps.
Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis.
DIFLUCAN 150mg 1 Caps. Interactions
1. Cimetidine: Decreased efficacy of fluconazole.
2. Cyclosporine: Increase in serum cyclosporine plasma concentration.
3. Hydrochlorothiazide: Reduction in renal clearance of fluconazole.
4. Phenytoin: Efficacy of phenytoin enhanced.
5. Rifampicin: Efficacy of fluconazole decreased, higher dosage required.
6. Sulfonylureas: Efficacy of tolbutamide, glyburide and glipizide increased.
7. Warfarin: Potentiates the anticoagulant effect resulting in increase in prothrombin time.
DIFLUCAN 150mg 1 Caps. Indications
1.Oesophageal candidiasis
2.Oropharyngeal candidiasis
3.Vaginal candidiasis
4.Systemic candidiasis
5.Cryptoc.
DIFLUCAN 150mg 1 Caps. alternatives in Egypt
| Medicine trade name | Company | price |
| ALKANAZOLE 150mg 1 Caps. | HIKMA PHARMA , EGYPT | ALKANAZOLE 150mg 1 Caps. |
| AMRIFLUCAN 150 mg 1 hard gelatin Caps. | AMRIYA , EGYPT | 5.5 LE for 1 Capsule |
| CANDEURAZOLE 150 MG 1 CAPS. | AL ANSAR FOR MARKETING , EGYPT | 12 LE for 1 capsules |
| DIFLUCAN 150mg 1 Caps. | PFIZER , EGYPT | 32.4 LE for 1 capsules |
| FLOCAZOLE 150mg 1 Caps. | EIMC , EGYPT | 21.6 LE for 1 capsules |
| FLUCORAL 150mg 2 Caps. | SEDICO , EGYPT | 17.52 LE for 2 capsules |
| FLUDCONRIZOLE 150mg 1 Caps. | RIVA PHARMA S.A.E. EGY. , EGYPT | 6 LE for 1 capsules |
| FUNGICAN 150mg 2 Caps. | AMOUN , EGYPT | 24 LE for 2 capsules |
| JENFUNGA 150 mg hard gelatin 1Caps. | JENIKO MEDICINE PHARMACEUTICALS , EGYPT | 4.5 LE for 1 capsules |
| RAMEFLUZOLE 150mg 1 Caps. | RAMEDA , EGYPT | 9.25 LE for 1 capsules |
| TREFLUCAN 150mg 1 Caps. | EIPICO , EGYPT | 10 LE for 1 capsules |
| TRICONAL 150mg 1 Caps. | T3A PHARMA , EGYPT | 18 LE for 1 capsules |
| UNIFUNGI 150mg 1 Caps. | UNIPHARMA CO. , EGYPT | 8 LE for 1 capsules |
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