DIFLUCAN 2MG/ML (50ML) I.V. INFUSION
Basic information about DIFLUCAN 2MG/ML (50ML) I.V. INFUSION
· Active content: FLUCONAZOLE.
· Price: 40 LE for 50 vial.
· Medical classification: antifungals.Triazoles.
· Company: PFIZER, EGYPT .
Mechanism of Action of DIFLUCAN 2mg/ml (50ml) I.V. infusion
Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis.
DIFLUCAN 2mg/ml (50ml) I.V. infusion Interactions
1. Cimetidine: Decreased efficacy of fluconazole.
2. Cyclosporine: Increase in serum cyclosporine plasma concentration.
3. Hydrochlorothiazide: Reduction in renal clearance of fluconazole.
4. Phenytoin: Efficacy of phenytoin enhanced.
5. Rifampicin: Efficacy of fluconazole decreased, higher dosage required.
6. Sulfonylureas: Efficacy of tolbutamide, glyburide and glipizide increased.
7. Warfarin: Potentiates the anticoagulant effect resulting in increase in prothrombin time.
DIFLUCAN 2mg/ml (50ml) I.V. infusion Indications
1.Oesophageal candidiasis
2.Oropharyngeal candidiasis
3.Vaginal candidiasis
4.Systemic candidiasis
5.Cryptoc.
DIFLUCAN 2mg/ml (50ml) I.V. infusion alternatives in Egypt
Medicine trade name | Company | price |
ANESTACON 2mg/ml (100ml) I.V. infusion | PHARMACELL , EGYPT | 56 LE for 100 vial |
DIFLUCAN 2mg/ml (50ml) I.V. infusion | PFIZER , EGYPT | 70 LE for 100 vial |
DIFLUCAN 2mg/ml (50ml) I.V. infusion | PFIZER , EGYPT | 40 LE for 50 vial |
FLUCAND 2mg/ml vial for inf. | HIKMA PHARMA , EGYPT | 60 LE for 1 vial |
FLUCTOBAR 2mg/ml vial for I.V. inf. | GLOBAL PHARMACEUTICAL INDUSTRIES , EGYPT | 30 LE for 1 vial |
NAVILUCA 2mg/ml vial for I.V. inf. | ROTABIOGEN FOR PHARMACEUTICAL INVEST. , EGYPT | 33.6 LE for 50 ml |
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